What's Different When Picking Up Professional Women?

In “How to Use Situationally Relevant Openers with Women”, a reader named Christopher made the following comment:

“Hello, Chase!
This post is great to develop your skill.
But, there was a situation I was stuck.An interesting one.
I was always successful with women since 2011, using simple and funny pickups. But I entered in an environment with high caliber women. They are very experienced and hard to control, but still show enough interest, so I can’t give up on them. I can’t say that there is no male concurrence. Real men with huge fundamentals.
So, could you write a post on a professional pickup, cause there have little effect on them.(they have seen a lot like this)”

It’s a little hard to follow, but if I’m reading it right Christopher’s recently run into a problem in that the approach he’s found success with picking up other kinds of women has fallen flat with professional (career) girls, who tend to be more used to holding their own around men and are frequently surrounded by plenty of ambitious and successful male options in their work and social lives.

And that’s actually a great observation (assuming I’m reading the comment right)... it IS quite different picking up professional women than other categories of women (students, retail / service industry workers, etc.).

They look for and respond to different things, and if you aren’t expecting that or aren’t calibrated to what women in the professional world are looking for, you can quickly be thrown for a loop.